CAMBRIDGE, MA – January 26, 2016 – Aurora BioPharma, Inc. CEO, Robert Brooks, will present promising CAR T Cell Therapy data in Solid Tumor from FDA Phase I Clinical trials in Glioblastoma and Sarcoma at the 18th Annual BIO CEO & Investor Conference taking place February 8-9, 2016 at The Waldorf Astoria New York. Aurora’s presentation time is as follows:
Event: BIO CEO & Investor Conference
Date: Monday, February 8th
Time: 11:15 am est
Room: Park North
Aurora is leading in the development of Chimeric Antigen Receptor (CAR) T therapy in solid tumors. AU105 is a “living-drug” CAR T agent that has shown safety and efficacy in pre-clinical and human clinical trials. A Phase 1 trial was completed in 16 Glioblastoma patients, AU105 met its endpoints of safety, tumor killing efficacy, and showed promising signals of increased overall survival. Aurora is planning a randomized multi-site Phase II trial of AU105 in Early Diagnosed Glioblastoma, and a Phase I/II trial in Recurrent Glioblastoma with intracranial injection. Osteosarcoma is the most common type of bone cancer in Children and Adolescents, even after radical amputation of a limb and chemotherapy, survival is poor. A Phase 1 trial in 19 Sarcoma patients was completed, AU-105 met its endpoints of safety, with strong signs of tumor killing efficacy. Aurora is planning a Phase II trial of its CAR T Cell therapy AU105 in Osteosarcoma. The Company also has an equity interest in MedVax Technologies, Inc., its p53 DC cancer vaccine MX-225 has completed two FDA Phase II clinical trials, in Small Cell Lung Cancer and Breast Cancer. The Company is planning a combination trial with MX-225 and a PD-1 antibody in lung cancer with a major pharmaceutical company. MX-225 is also in a Phase II combination trial in breast cancer with Indoximod, an IDO inhibitor from NewLink Genetics.
The BIO CEO & Investor Conference is one of the largest investor conferences attracting investment bankers, industry analysts, and biotechnology executives who delve into relevant business models, deal-making, and investment options in the life sciences. This year’s conference features presentations by over 140 leading biotechnology and pharmaceutical companies, as well as nonprofit and venture philanthropy organizations.
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New Paradigm in Cancer Immunotherapy
Source: Aurora BioPharma, Inc.