TECHNOLOGY

Aurora’s “Bionic” T Cells : CAR T-Cells engineered to kill cancer

The human body has a powerful immune system, and one of its white blood cells called a T-cell is like a solider capable of attacking and killing abnormal cancerous cells. However, in cancer patients, these T cells are compromised, either fail to target or recognize cancerous cells, or are too few in number to lead an strong attack. Aurora’s revolutionary CAR T Cell Therapy change a cancer patient’s own weak T cells into “bionic” killing machines —a highly targeted army that can kill cancer. A cancer patient’s T cells are removed from a blood draw, genetically engineered in a laboratory, expanded to almost a billion CAR T cells, and re-infused back into the patient where they are better able to kill cancer.

Courtesy of Nature Magazine

Aurora’s Revolutionary CAR T cell Clinical Cancer Trials

Aurora’s CAR T Cells have been shown to kill multiple types of solid tumors in pre-clinical animal studies, and in completed human trials. In two completed Phase I/II clinical trials in Sarcoma and Glioblastoma, our revolutionary CAR T Cell therapy AU101 and AU105 showed it can be safe, produce tumor killing and increase survival.

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Preclinical

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Sarcoma

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Glioblastoma

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